successfully differentiated from the iPSCs and approximated the gene expression profiles of the primary hepatocytes more closely than the profiles of the livers (Figure S3B). We specifically assessed the expression levels of six hepatocyte-specific genes in the HLCs (Figure S2B), using these levels as compared to levels in primary human hepatocytes as a means to assess the quality of the HLCs (scored from zero to five) (Table S1).
