In this article we follow-up on evidence for linkage on chromosome 2 with alcohol dependence [Foroud et al., 2000; Wilhelmsen et al., 2005], conduct disorder [Dick et al., 2003; Kendler et al., 2006a], and suicide attempts [Hesselbrock et al., 2004; Zubenko et al., 2004; Willour et al., 2007] in the COGA sample, and independent samples [Zubenko et al., 2004; Kendler et al., 2006b; Willour et al., 2007]. These phenotypes have shown consistent linkage to the centromeric region of chromosome 2 across multiple samples. In addition, there have been linkages reported to alcohol and related phenotypes on the p and q arms of chromosome 2 [Straub et al., 1999; Goode et al., 2003; Wang et al., 2005; Wiener et al., 2005; Wilhelmsen et al., 2005; Kuo et al., 2006; Agrawal et al., 2008]. We find that the phenotype of alcohol dependence with either conduct disorder or suicide attempts results in a maximum LOD score of 5.4 in the centromeric region of chromosome 2. Although the joint phenotype of AD or CD or SUI produced a similar LOD score in the microsatellite
