As expected, bipolar I Individuals with depression and manic episodes reported receiving significantly more often professional help independent of a comorbid Cannabis use disorder. Comorbid bipolar I individuals also reported a higher number of affective symptoms. General psychosocial functioning was higher in bipolar II vs. bipolar I patients, independent of comorbid CUD. As also presented in Table 4, no differences were found across groups regarding the number of mixed episodes, rapid cycling, and suicidal ideation and behavior.