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Chunk #71 — BRAIN STIMULATION TECHNIQUES AND NETWORK ANALYSIS IN NEUROPSYCHIATRIC DISEASE — Schizophrenia

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Exploration and modulation of brain network interactions with noninvasive brain stimulation in combination with neuroimaging.
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an increase in functional connectivity in the contralateral cortex and frontal areas) suggesting a mechanism for observed behavioral effects. A more recent study using resting-state fMRI (Vercammen et al., 2010b) also found that rTMS altered brain connectivity by significantly increasing the functional connectivity between the targeted left temporo-parietal junction and the right insula. However, there was no change in the strength of the specific connections that were previously shown to be correlated with symptom severity (Vercammen et al., 2010a), suggesting that further work needs to be done to determine the role of these different interactions in the pathophysiology of schizophrenia.