The primary focus of this study was to introduce the Add Health sibling pairs subsample genome-wide association data and conduct initial analyses to demonstrate the scientific potential of the data as a resource to the Add Health community of researchers. Given the unconventional (among traditional genome-wide studies) Add Health pairs subsample, we adopted a relatively unconventional approach to carry out the genome-wide analysis. First, it is estimated that 96% of all genome-wide studies have been conducted on people of European descent (Bustamante et al., 2011). The reasons and explanations for focusing so exclusively on samples of European descent range from convenience and efficiency (using existing cohort studies that focus on subjects of European descent) to minimizing sources of genetic heterogeneity (Pulit et al., 2010; Bustamante et al., 2011). However, recently, there has been a series of studies that have empirically demonstrated a critical role of multiethnic studies in genome research of complex disease(Pulit et al., 2010; Masunuru et al., 2012; Carlson et al., 2013; Gong et al., 2013; Manichaikul et al., 2012; Manku et al., 2013; Marigorta et al., 2013;
