Chunk #37 — Discussion — Cross-disorder genome-wide association study of ASD and schizophrenia

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Meta-analysis of GWAS of over 16,000 individuals with autism spectrum disorder highlights a novel locus at 10q24.32 and a significant overlap with schizophrenia.

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We extended our analyses to perform a cross-disorder ASD and schizophrenia meta-analyses to identify putative neurodevelopmental loci; again, we utilised the ASD GWAS excluding known shared controls. We identified 12 GWS loci not previously identified as GWS in the PGC schizophrenia GWAS.