According to Table 8 , though the sample size may be reduced, we still recommend limiting dosage probabilities before genotyping. In our experience, a threshold at 0.7 ∼ 0.8 level can be a good cut-off. A threshold lower than this level may contribute too much noise and a threshold higher than this may reduce the sample size significantly. Meanwhile, we suggest interpreting the dTDT signals only after genotyping validation in order to lower the risk of false positives.