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Chunk #20 — 2. Materials and Methods — 2.5. DMN Seed Regions and FC Calculations

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Random Forest Classification of Alcohol Use Disorder Using EEG Source Functional Connectivity, Neuropsychological Functioning, and Impulsivity Measures.
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The DMN regions analyzed in the study are posterior cingulate cortex (PCC), anterior cingulate cortex (ACC), inferior parietal cortex (IPL), prefrontal cortices (PFC), lateral temporal cortex (LTC), and hippocampal formation (HCF) (Table 2 and Figure 1), in line with the fc-MRI and fc-EEG studies [58,78,79,80]. More information about the DMN seed selection is described in our recent publication with fc-MRI in the same sample as the current study [54]. Each seed region contained the voxels within 10 mm radius from the peak/centroid point of the region. The ROI-to-ROI connectivity [81], the most commonly used method to derive FC across brain regions [82], was computed using the exact low resolution electromagnetic tomography software (eLORETA) software [42], as described in the next section.