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Chunk #3 — Results — Psychiatric genetics factors and biobehavioral traits.

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Genetic architecture of 11 major psychiatric disorders at biobehavioral, functional genomic and molecular genetic levels of analysis.
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Using a Bonferroni correction for 174 tests, 7/49 correlations with biobehavioral traits were significant for Qtrait for the Compulsive factor, 18/49 for the Psychotic factor, 39/49 for the Neurodevelopmental factor, 17/49 for the Internalizing factor, and 38/49 for the p-factor (Fig. 3 and Supplementary Table 5). Excluding genetic correlations significant for Qtrait, and using the same Bonferroni correction, 17 genetic correlations were significant for the Compulsive factor, 12 for the Psychotic factor, five for the Neurodevelopmental factor, 20 for the Internalizing factor, and three for the p-factor. We provide a more detailed assessment of significant correlations in the Supplementary Note.