Atypical patterns of physical movement throughout the 24-hour cycle may reflect disturbances in basic homeostatic processes that confer transdiagnostic psychiatric risk31. Using accelerometer data from UK Biobank30, we examined genetic correlations between the individual psychiatric traits and factors and physical movement across a 24-hour period (Fig. 4 and Supplementary Table 6). One correlation was significant for Qtrait for the Compulsive factor, two for the Psychotic factor, 12 for the Neurodevelopmental factor, seven for the Internalizing factor, and 18 for the p-factor. Excluding significant Qtrait correlations, eight correlations were significant for the Compulsive factor, four for the Psychotic factor, one for the Neurodevelopmental factor, six for the Internalizing factor, and two for the p-factor.
