Survival analysis of alcohol initiation revealed that only SA increased risk for alcohol initiation prior to the age of 14 in EAs [HR=1.43 95%CI: (1.08–1.87)] with no association of SA with alcohol initiation in AA women and no further significant increase in hazards of other types of trauma exposure in EA or AA women (Table 2). When considering the contribution of other substances, in EA women, the largest magnitude risk for alcohol initiation was conferred between the ages of 14 and16 by tobacco use [HR= 2.97 95%CI: (2.64–3.33)] and cannabis use [HR= 1.88, 95%CI: (1.70–2.09)] prior to the age of 16. For AA women, tobacco use increased the hazard for alcohol initiation with the highest magnitude prior to the age of 17 [HR= 2.30, 95%CI: (1.67–3.17)] with the increased hazard conferred by cannabis use [HR= 2.26, 95%CI: (1.76–2.90)] consistent across all risk periods. Posttraumatic stress disorder did not significantly increase the hazard for alcohol initiation in EA or AA women.