Finally, the estimates of genetic correlations among metabolic traits are consistent with the estimates obtained using REML in Vattikuti et al. [15] (Supplementary Table 6), and are directionally consistent with the recent Mendelian randomization results from Wuertz et al. [55]. The estimate of 0.54 (0.07) for the genetic correlation between CD and UC is consistent with the estimate of 0.62 (0.04) from Chen et al. [16].
