For the current analyses, phenotypic and genetic data were drawn for replication from 1428 cases and 506 neighborhood controls. Principal components (PCs) created in SmartPCA35 from all SNPs were used to control for ethnic admixture. For each outcome (anhedonia, depression, anhedonic depression) one PC was identified as significant (p-0.03–0.04) and consequently all logistic regression analyses included this PC as a covariate.
