Chunk #27 — RESULTS — Associations between AUDIT PRS and consumption measures — COGA:

Source

Polygenic contributions to alcohol use and alcohol use disorders across population-based and clinically ascertained samples.

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yes

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As shown in Table 2, only the AUDIT-P PRS was significantly associated with monthly alcohol use (R2= 0.65%, p = 1.24e-4) and MaxDrinks (R2= 0.47%, p = 2.00e-8). We also converted the pseudo-R2 values for all binary outcomes to R2 on the liability scale (Lee et al., 2012), but as estimates did not differ, these results are not presented.