The previously indicated polymorphisms in the DAT1 and COMT gene were not associated with either borderline or antisocial traits in the US young adult sample (Table 2). However, both the DRD2 B1-allele and A1-allele were significantly associated with borderline traits (TaqIB 3 genotypes: χ2 = 14.935, df = 2, p = 0.001, B1+ vs B1- categories: χ2 = 12.977, df = 1, p = 0.0003; TaqIA 3 genotypes: χ2 = 10.568, df = 2, p = 0.005, A1+ vs A1- categories: χ2 = 9.477, df = 1, p = 0.002). These associations remained significant after correcting for multiple comparisons (p < 0.0056). Subjects carrying at least one B1-allele were six times more likely to develop borderline symptoms, OR = 6.2 (2.15-17.85), whereas A1+ subjects were five times more likely to have borderline symptoms, OR = 5.17 (1.7-15.7). Similar results were found in the Caucasian subgroup (N = 66): TaqIB 3 genotypes: χ2 = 15.415, df = 2, p = 0.0004; B1+ vs B1- categories: χ2 = 14.139, df = 1, p = 0.0002, OR = 10.1 (2.7-37.6). TaqIA 3 genotypes:
