Chunk #24 — 3. Results — 3.6. Fenofibrate treatment initiated after LPS injection does not attenuate neuronal injury

Source

Effects of chronic systemic treatment with peroxisome proliferator-activated receptor α activators on neuroinflammation induced by intracerebral injection of lipopolysaccharide in adult mice.

Embedded

yes

Text

To examine the effect of post-LPS treatment with fenofibrate, fenofibrate treatment was initiated at 15 minutes after completing LPS injection and followed by daily administration until the brain was collected. No influence by fenofibrate was observed on lesion volume at 3 days after LPS (Fig. 7D).