However, the study also has some limitations. For instance, our study features a small sample size and lacks a control group for the cue-reactivity paradigm. Future studies focusing on these two primary limitations and confirming the results with resting state fMRI functional connectivity and task-based EEG may be able to confirm the presence of a craving network. These results also pave the way for other network-based approaches such as correlation analysis, directed functional connectivity, dynamic functional connectivity, etc. to confirm the correlates of pathological craving. Nevertheless, the current study is one of the first to combine resting-state EEG and cue-based fMRI to present the neural correlates of substance craving with superior spatial and temporal resolution and propose a substance-general craving network.
