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Chunk #17 — 2 Brain Function Responses to Acute Nicotine Administration and Cigarette Smoking — 2.3 Brain Dopamine Responses to Nicotine and Smoking

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In vivo brain imaging of human exposure to nicotine and tobacco.
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Other functional imaging studies of the DA system have reported decreased D1 receptor density (Dagher et al. 2001), increased 18F-DOPA uptake (a marker for increased DA turnover) (Salokangas et al. 2000), and both decreased (Krause et al. 2002) and no alterations (Staley et al. 2001) in dopamine transporter binding in smokers.