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Chunk #50 — Some conclusions and future directions

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A Critical Review of Methods and Results in the Search for Genetic Contributors to Alcohol Sensitivity.
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This review has several implications for my own future work. With my interest in evaluating why only some relatively problem-free lighter drinkers escalate their intake and problems, I will continue to include both single dose oral alcohol challenges and retrospective self-reports of drinks needed for effects. While higher stimulation early in the alcohol challenge has rarely been observed using our own paradigms, in future work I will add stimulation measures to our current measures of overall feelings of alcohol intoxication. Our own findings might reflect the fact that my testing paradigm involves slowly rising BACs and the major subjective measure used, the SHAS, is not as likely to pick up stimulation as the BAES that was developed years after my research began.