While ERPs have been successfully recorded in a number of animal species the use of ERO technology to study brain function in animal models has been less applied. Schurmann et al.(2000) reported that event-related alpha oscillations could be observed in cats in response to visual stimuli in specific sensory pathways and also in the hippocampus. Evoked gamma oscillations have been reported in mice that were enhanced by nicotine and blocked by pretreatment with mecamylamine (Phillips et al., 2007). In the present report the effects of stimulus characteristics on the generation of EROs in the .5-35 Hz frequencies was evaluated. The results of these studies demonstrate that EROs can be generated in cortical sites in mice in the delta, theta, alpha/beta frequency ranges in response to auditory stimuli. Oscillations in the 7.5-40 Hz frequencies were significantly affected in the 0-50 msec time range in response to differences in tone frequency. Whereas, changes in tone loudness produced changes in oscillations in the 7.5-40 Hz frequencies in the 350-800 msec range. No significant changes in EROs were found to differences in tone probability.
