of the longest running prospective studies in the United States using a comprehensive and detailed assessment of the domain and facets of the five-factor model of personality. Second, we pooled findings from published studies and performed meta-analyses to summarize evidence for the association of personality traits with incident AD. Based on previous research, we expected that high conscientiousness (those who are organized and have more self-discipline and willpower) and low neuroticism (those who are less likely to be anxious, depressed, and vulnerable to stress) would be associated with a reduced risk of incident AD.