The rapid adoption of next generation sequencing technologies is also having a major impact on variation data in Ensembl. Whereas data continues to be imported from dbSNP, a major new source of computationally discovered variation data is from the processing of resequencing data. This second data source is growing rapidly in parallel with next generation sequencing technology. This year, Ensembl imported the data from three successive builds of dbSNP (127, 128, and 129). It has also incorporated resequencing-based SNPs from platypus and orangutan and as well as from the resequenced human genomes of Watson and Venter. The playpus SNPs were submitted to dbSNP and make up the largest set of SNPs for that species. The orangutan SNPs will be submitted in conjunction with the publication of that genome.
