intervention-targeted parenting as a function of SAAF participation. Although this is not directly relevant to the differential susceptibility hypothesis, it is relevant to the broader issue of optimal construction of preventive intervention programs. The availability of parent genotypes provided an opportunity to explore this hypothesis. Given prior work indicating that youth 5HTT predicts differential initiation of risk behavior (Brody, Beach, Philibert, Chen, & Murry, 2009), we entered this genetic polymorphism into our analyses of youth susceptibility to the parenting intervention as a control variable.