Chunk #65 — ONLINE METHODS — Bayesian credibility analyses

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Genetic variants associated with subjective well-being, depressive symptoms, and neuroticism identified through genome-wide analyses.

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Using this equation, we can calculate the probability that the GWAS estimates will have concordant signs across the two phenotypes, or that the GWAS estimate of the second-stage phenotype will reach some level of significance. These probabilities can be summed over the set of lead SNPs to generate the expected number of SNPs meeting the criterion.