Chunk #66 — ONLINE METHODS — Bayesian credibility analyses

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Genetic variants associated with subjective well-being, depressive symptoms, and neuroticism identified through genome-wide analyses.

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To obtain effect-size estimates for a SNP that are adjusted for the winner’s curse (Supplementary Table 32), we use the mean of the posterior distribution of the SNP’s effect, conditional on the quasi-replication result and the SNP being non-null. We derive the posterior distribution and expected R2 in the Supplementary Note.