As an incidence analysis, we examined the association of early onset tobacco use with suicide ideation among those 615 females who did not report any suicidal thoughts at baseline. Those with early regular tobacco use had a higher liability to incident suicidal ideation at the age of 22 compared to never users. In the fully adjusted model early-onset tobacco use remained significantly associated with incident suicidal ideation (OR 2.72, 95%CI 1.05–7.06, p=.039) (not shown in tables).