For age of regular tobacco use initiation, there was a sex interaction (Likelihood-ratio test LR chi2 (2) = 5.21; p= .074), so that the association of early onset tobacco use was significant among females only. Females with early-onset regular tobacco use had a higher liability to suicidal ideation at the age of 22 compared to never users. When adjusted for multiple confounders early onset tobacco use remained significantly associated with subsequent suicidal ideation (AOR 3.69, 95%CI 1.56–8.72, p=.003) (Table 1).
