For the genome-wide significant loci from the overall meta-analysis, we explored potential causative genes at each association locus using the PrixFixe method74, assuming co-function of all significant loci. As required by the PrixFixe method, we assured our genome-wide significant loci were present in dbSNP v13775 and were represented HapMap76 phase III data; for loci not meeting these requirements, proxy SNPs from HapMap phase III were selected based on strongest LD (r2) with index SNP (see Supplementary Table 11 for details of the proxy variant used at each genome-wide significant locus).
