paperKB
coga / coga-kb
Processing
Help
Sign in

Chunk #19 — Online Methods — COPD comorbidity overlap analysis

Source
Genetic loci associated with chronic obstructive pulmonary disease overlap with loci for lung function and pulmonary fibrosis.
Embedded
yes

Text

We assessed the overlap between our results and two common COPD comorbidities, coronary artery disease and osteoporosis (through bone mineral density traits). We downloaded information on genome-wide significant (P < 5×10−8) associations with these comorbidities as reported in the NHGRI-EBI GWAS Catalog42. We assessed the association statistics of these comorbid trait loci in our Stage 1 meta-analysis results.