Glutamatergic inhibition of network activity significantly reduced the percentage of active neurons (p < 0.0001 for all time points) and their synchronicity (p < 0.05 for all time points). The bursting frequency was reduced as well, although only at week 5 (p < 0.001) while the bursting amplitude remained unaffected on all time points (p = NS) (Fig. 5a). Representative traces are shown in Fig. 5b.
