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Chunk #5 — 1 Introduction

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Genetic factors modulating the response to stimulant drugs in humans.
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We will attempt to synthesize genetic studies of acute, sub-chronic, and chronic administration of stimulant drugs in this review. First, we will discuss overall heritability of stimulant drug-related phenotypes based on twin studies. Next, we will discuss candidate gene and genome-wide association studies that implicate specific genes in modulating responses. Last, we will highlight the key conclusions and identify future directions for study.