There were two GABRG1 haplotype blocks with a recombination region in intron 2 (Figure 3). Block 1 extended from the GABRA2-GABRG1 intergenic SNP rs4695146 to the intron 2 SNP rs17536211, a distance of 83.2 kb. There were 9 haplotypes (≥ 0.01 frequency) that accounted for 0.96 of the haplotype diversity. From Figure 3 it can be seen that haplotypes H1 and H2 differed by only one allele and were more abundant in alcoholics than non-alcoholics (0.45 vs 0.36). In contrast, haplotypes H8 and H9, differing by only one allele, were more common in non-alcoholics compared with alcoholics (0.49 vs 0.41): (H1 + H2) vs (H8 + H9): χ2 = 8.3, 1 df, p = 0.0039.
