In conclusion, the present study finds that there is high comorbidity of SUD in Latinos (particularly men) with SC, and that this varies across countries. Male gender and history of depression are important risk factors for comorbidity in these Latino populations. The substances of abuse/dependence that are most frequent are alcohol, cannabis, solvents, and cocaine. The sequence of onset of SUD in comorbid cases also suggest that potential preventative strategies may be of use in men (prior to onset of SC) and that SUD prevention in women may be especially important after the development of SC. Further exploration and study of the “protective” aspects of Latino culture in Latino countries and the increased risk associated with Latinos living in the US will be valuable in treating and preventing SUD in subjects with SC.
