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Chunk #32 — DISCUSSION

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Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals.
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Second, we found that our score for EA has much lower predictive power in an African-American sample than in a European-ancestry sample, and we anticipate that the score would also have reduced predictive power in other non-European-ancestry samples. Therefore, until polygenic scores are available that have as much predictive power in other ancestry groups, the score will be most useful in research that is focused on European-ancestry samples.