CNV loci and half of these CNVs are of sizes from 1 to 10 kb. The frequency spectrum and the precise structure of CNVs are closely related to the technical and algorithmic methods applied (12,13). Specific CNVs have been related to a number of complex traits–examples are psoriasis (14), schizophrenia (15), autism (16), developmental disorders (17) or HIV1/AIDS susceptibility (18). In some instances, particular CNVs were related to certain disorders as de novo events [e.g. schizophrenia (15)].
