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Chunk #8 — Methods and Materials — Genotyping and Analysis

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Genome-wide association study identifies new susceptibility loci for posttraumatic stress disorder.
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We first performed GWAS analyses on all subjects after quality control with logistic regression models, adjusted by the first four MDS factors, sex, and age. European Americans and AAs were analyzed separately. To evaluate the influence of trauma exposure specifically, we restricted the GWAS analyses to subjects with self-reported trauma experiences. In this secondary analysis, the covariates of MDS factors, sex, and age were the same as the primary analysis.