We estimated the local ancestry around the two TLL1 SNPs (rs6812849 and rs7691872) of all GWAS AA subjects using the HAPMIX program (27). Logistic regression tests of the two TLL1 SNPs and PTSD in AAs were performed after adjustment for age, sex, and local European ancestry scores. The detailed information of estimating local ancestry is provided in Supplemental Methods in Supplement 1.