et al., 2008; Zhang et al., 2006). In addition, these effects in SAGE were similar to the findings in the individual three studies that contributed to SAGE: COGA, FSCD and COGEND. Across the three contributing studies, the odds ratios ranged from 1.07-1.13 for rs1800497 in DRD2, 1.06-1.11 for rs698 in ADH1C, 0.82-0.95 for rs1799971 in OPRM1, 1.09-1.17 for rs279858 in GABRA2 and 1.02-1.09 for rs4680 in COMT (data not shown).
