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Chunk #10 — Adenosine, Receptors and Functions in the CNS

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Purinergic Receptors of the Central Nervous System: Biology, PET Ligands, and Their Applications.
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Provided the roles of A1 and A2A receptors in brain pathologies, the availability of scientific tools such as specific PET radioligands for evaluation of these receptors functions under normal and pathophysiological conditions would be desirable and could help elucidate novel therapeutic strategies.75