Frontoparietal connectivity in FHP and FHN youth was examined by using fcMRI maps (corrected for multiple comparisons, >24 contiguous voxels each at p<.05) representing the correlation between: right PPC to right DLPFC, left PPC to left DLPFC, right PPC to left DLPFC, and left PPC to right DLPFC, plus exploratory analyses examining correlations of the seed regions to all other voxels in the brain, for each subject. Single sample t-tests evaluated the extent to which these correlations differed from zero for each FH group. FHN youth showed positive correlations between BOLD response time series in: right PPC with right PPC [mean r = .53, p < .001], left PPC with left DLPFC [mean r = .33, p < .001], right PPC with left DLPFC [mean r = .24, p < .001], and left PPC with right DLPFC [mean r = .35, p < .001]. In contrast, the FHP youth exhibited positive correlations between the right PPC and right DLPFC [mean r = .39, p < .001] and left PPC and right DLPFC [mean r = .26, p < .001]. Independent
