transformation of the time domain signals; frequency shift correction, phase correction and baseline correction. The fitting error was automatically computed as a deviation between theoretical and measured spectrum determined using the last squares method. Values less than 0.5 were considered satisfactory, however, in the whole group mean fitting error was 0.36 (SD, standard deviation 0.07). The following metabolites were assessed: NAA, Glx, mI, Cho and Cr. No absolute concentrations of metabolites were determined, but their ratios to Cr and Cho.