Chunk #40 — Materials and Methods — Data preprocessing — Single nucleotide polymorphism data preprocessing – primary study

Source

MicroRNA expression in abdominal and gluteal adipose tissue is associated with mRNA expression levels and partly genetically driven.

Embedded

yes

Text

Samples were genotyped using the Illumina 317 k Beadchip platform. One sample was removed due to non-European ancestry. SNPs were excluded if MAF<1% or if genotyping success rate was <95% and MAF >5%, and if genotyping success rate was <99% and MAF <5%. Hardy-Weinberg equilibrium was calculated by combining all unrelated and SNPs were removed if HWE p-value was <0.0001. In total, 69 samples were successfully genotyped for 302765 SNPs.