Chunk #41 — Materials and Methods — Data preprocessing — Single nucleotide polymorphism data preprocessing – replication study

Source

MicroRNA expression in abdominal and gluteal adipose tissue is associated with mRNA expression levels and partly genetically driven.

Embedded

yes

Text

Completely failing assays (<25% success rate) were first removed. Thereafter samples with <85% success rate were removed. Hardy-Weinberg equilibrium was calculated, and SNPs with HWE p-value <0.001 or success rate <85% were excluded from further analysis.