The utility of the DGIdb as a resource is reflected in its substantial web and especially API traffic. The website receives ∼1700 unique users and ∼2800 sessions a month, an increase of 42 and 39%, respectively, since the initial release of the DGIdb. Additionally, 42% of unique visitors within the past year were returning users. Within the last year, the DGIdb API has been used by 3689 unique IP addresses for a total of 939 429 requests, as seen in Supplementary Figure S4. At the time of publication, 2.0 was used by a number of bioinformatics tools in the development of their platforms. DGIdb has since been integrated into four additional tools, bringing the total number of known platforms that utilize the DGIdb to 10. These platforms are GeneCards (http://www.genecards.org), CVE (20), rDGIdb (21), PANDA (22), iCAGES (icages.usc.edu), BioGPS (23), Omics Pipe (24), GEMINI (25), StationX (www.stationxinc.com) and IHLDB.rf (www.lungcancerdatabase.com). These integrations highlight the accessibility and utility of the DGIdb API, which has been expanded to include new endpoints in 3.0.