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Chunk #18 — Results — Statistical analysis of pooled data — Single marker tests

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Genome-wide significant association between alcohol dependence and a variant in the ADH gene cluster.
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Comparison with AD GWAS data from the COGA, SAGE, and OZ-ALC samples obtained through dbGAP (Mailman et al. 2007) showed that the SNP rs1789891 had also shown nominal significance in the COGA GWAS (p=1.47E–2), and that the same allele had been associated with AD. No significant association with this variant was found in the SAGE- or the OZ-ALC sample (Table 2).