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Chunk #15 — Materials and Methods — Subjective response Assessment Instruments

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Independent and Interactive Effects of OPRM1 and DAT1 Polymorphisms on Alcohol Consumption and Subjective Responses in Social Drinkers.
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During the alcohol sensitivity procedure, subjects completed the Biphasic Alcohol Effects Scale (BAES) (Martin et al., 1993), the 13-item Subjective High Assessment Scale (SHAS) (Schuckit, 1980), Profile of Mood State Tension and Anxiety (POMS-TA) subscale (McNair et al., 1992), and the Drug Effects Questionnaire Visual Analog Scale (DEQ VAS) (McCaul et al., 1990, Preston and Bigelow, 1991) using a laptop computer (see Supplemental Methods A.). For all instruments, subjects rated each item on how they felt “right now” at eight time points over a 5-hr period: at baseline (−25 min), five minutes after consumption of the placebo drink (+15), and each alcohol drink (+60, +105, +150 min), and at 45-minute intervals for the remainder of the session (+195, +240, +285 min).