Hill et al. (2007a) found a significant increase in grey matter and a tendency for total volume of the cerebellum to be increased in adolescents and young adults at high risk for AUD. Age regression of the grey matter volumes suggested a slower reduction in grey matter volumes among the offspring of alcoholics that may indicate a delay in grey matter pruning or slower maturational increases in white matter. Benegal et al. (2007) also found differences in cerebellar volume in high risk alcohol-naive subjects using both region of interest and voxel-based morphometric analyses. Compared to controls, high risk subjects also had decreased grey matter volume in the thalamus, superior frontal gyrus, and cingulate gyrus.
