To assess the degree to which rs9829896 association with drug abuse was a general effect or driven by abuse of a specific drug, we tested rs9829896 for association with each illicit drug category separately. As shown in Table 3, the rs9829896-C allele was significantly and consistently associated with reduced risk of abuse for all drug categories in the meta-analysis of UHS and GAIN AAs, with degree of significance varying largely by the number of cases available by illicit drug category and thus reflecting reduced statistical power (Table S13).