of the peak amplitude of fEPSP (second stimulation) / fEPSP (first stimulation). LTP will be induced by four tetani delivered 20 s apart, each at 100 Hz for 1 s after a 20 minutes baseline period. fEPSPs were monitored for 60 minutes after tetanus. The raw data was collected and analyzed by using pClamp 10 software (Molecular Devices, Sunnyvale, CA, USA).