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Chunk #5 — METHODS

Source
Pharmacotherapy effects on smoking cessation vary with nicotine metabolism gene (CYP2A6).
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yes

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(2) bupropion SR (150mg twice daily for 9 weeks total: 1 week prior to the quit date and 8 weeks post-quit); (3) nicotine replacement therapy including nicotine lozenge (2 or 4 mg based on the package insert instructions for 12 weeks post-quit), nicotine patch (24-hour patch; 21, 14, and 7 mg; titrated down during 8 weeks post-quit), or nicotine patch + nicotine lozenge combination therapy (dosed as listed above), and (4) combined bupropion SR and nicotine lozenge therapy (dosed as listed above). In addition, all participants received six brief (10 minute) individual counseling sessions.